MALDI-TOF/TOF

Equipment



MALDI-TOF/TOF
Applied Biosystems/MDS Sciex
4800 MALDI TOF/TOF analyzer

The 4800 MALDI TOF/TOF Analyzer is a floor-standing mass spectrometer that delivers high resolution and accurate mass determination for the MS analysis of biomolecules including protein digests, intact proteins, lipids, and carbohydrates. The system also enables the precise selection of individual precursor masses for further fragmentation enabling definitive identification and characterization for these biological molecules by MS/MS.

  • MALDI (matrix assisted laser desorption ionization) instrument features tandem time-of-flight (TOF/TOF) analyzers
  • Variable ion path length to accommodate MS linear, MS reflector and MS/MS modes
  • Nd:YAG laser operates at 355nm to ionize samples
    positive and negative ion detection
  • High-resolution precursor selection (MS/MS mode)
  • Automated single-plate sample-loading system
  • Software: 4000 Series Explorer V3.5.3 ( Build 1017)

Research Facility



Mass Spectrometry Facility - Centre for Chemical Analysis, Research and Training (C-CART) - CREAIT Network
Memorial University
St. John's
Newfoundland and Labrador (NL)

The facility has five mass spectrometers with a number of sample introduction options (GC, LC and CE), ionization sources and analyzer types to allow analysis over a large mass range from small molecules to large proteins. Three of the instruments have TOF (time-of-flight) analyzers providing high sensitivity and resolution for accurate mass determinations. The LCMS systems have the option of ESI,APCI or APPI ionization sources.

Potential users of the facility are encouraged to meet with the operator prior to training to discuss the scope and nature of their work to determine the most appropriate instrument choice. Access to the lab is limited to 9:00am to 5:00pm Monday to Friday. More experienced users may request 24/7 access.

  • Biological and Life Sciences
  • Biomedical
  • Chemistry and Biochemistry
  • Engineering - Agricultural, Forest, Environmental, Mining, Mineral
  • Engineering - Chemical, Nuclear, Other
  • Environmental and Earth Sciences
  • Marine/Ocean Sciences
  • Medical Sciences
  • Biomedical
  • Agriculture, Animal Science and Food
  • Chemical Industries
  • Clean Technology
  • Consumer Non-Durables
  • Education
  • Energy (Renewable and Fossil)
  • Environmental Technologies and Related Services
  • Fisheries and Aquaculture
  • Forestry and Forest-Based Industries
  • Health Care and Social Services
  • Life Sciences, Pharmaceuticals and Medical Equipment
  • Mining, Minerals and Metals
  • Ocean Industries

Contacts



Linda Winsor Primary Contact
7098643052
Research Laboratory Coordinator
Brent Myron
7098646798
Manager of Operations - CREAIT Network

Date submitted: Wed, Oct 19, 2016 11:16 PM
Date updated: Wed, Oct 19, 2016 11:17 PM

2018-04-09T04:35:14+00:00