Liquid Chromatography Tandem Mass Spectrometry with Ion Mobility

Equipment



Liquid Chromatography Tandem Mass Spectrometry with Ion Mobility
Dionex - ABSciex
Ultimate 3000 UHPLC Qtrap 5500 with Selexion Source

The Qtrap5500 LC/MS/MS system (AB SCIEX) is designed to excel at detection and confirmation of low-level analytes, and can be specifically used for quantification, verification and validation of  protein/peptide biomarkers. The QTRAP® 5500 system houses a linear ion trap with ultra-fast scan speeds of up to 20,000 Da/s. The flexibility of this system allows a variety of acquisitionmodes, including high-sensitivity full-scan MS, MS/MS, and MS3 capabilities. High-selectivity can be achieved from true triple quadrupole precursor ion (PI) and neutral loss (NL) scans. Accurate and precise quantitation can be obtained by selected reaction monitoring (SRM, also known as Multiple Reaction Monitoring, MRM) using the high-sensitivity triple quadrupole configuration. Furthermore, the QTRAP 5500 is equipped with a differential ion mobility source. This novel SelexION™ Technology device delivers a new dimension of selectivity and performance for applications requiring the separation of isobaric species, elimination of challenging co-eluting contaminants and reduction of high background noise.

2011

Research Facility



Proteomics and Metabolomics Core Facility
Dalhousie University
Halifax
Nova Scotia (NS)

The Proteomics and Mass Spectrometry Core Facility (PCF) forms part of Dalhousie's CORES(Centralized Operation of Research Equipment and Support) program. The laboratory is located in the Life Sciences Research Institute (LSRI) and offers a full range of proteomics/metabolomics mass spectrometry (MS) based analytical services to Dalhousie’s scientific community and external clients. The laboratory is run by experts with more than 20 years of experience in MS who provide technical expertise and one-on-one support. The experiments and results generated in the lab have contributed to a long list of peer-reviewed publications. Check the FAQs section for commonly asked questions regarding sample submission. For more information on pricing or how to schedule an analysis, contact the PCF at (902) 494-8359 or proteomics@dal.ca​​​.

  • Biological and Life Sciences
  • Biomedical
  • Chemistry and Biochemistry
  • Biomedical
  • Biotechnology
  • Agriculture, Animal Science and Food
  • Education
  • Life Sciences, Pharmaceuticals and Medical Equipment

Contacts



Alejandro Cohen Primary Contact
9024948359
Scientific Director
Carla Ross
9024941887
Director of Research Development

Date submitted: Mon, Sep 18, 2017 5:01 PM
Date updated: Tue, Sep 19, 2017 9:41 AM

2018-04-09T04:40:04+00:00